Gene delivery system for multidrug-resistance
نویسندگان
چکیده
منابع مشابه
Optimization of conditions for gene delivery system based on PEI
Objective(s): PEI based nanoparticle (NP) due to dual capabilities of proton sponge and DNA binding is known as powerful tool for nucleic acid delivery to cells. However, serious cytotoxicity and complicated conditions, which govern NPs properties and its interactions with cells practically, hindered achievement to high transfection efficiency. Here, we have tried to optimize the properties of ...
متن کاملoptimization of conditions for gene delivery system based on pei
objective(s): pei based nanoparticle (np) due to dual capabilities of proton sponge and dna binding is known as powerful tool for nucleic acid delivery to cells. however, serious cytotoxicity and complicated conditions, which govern nps properties and its interactions with cells practically, hindered achievement to high transfection efficiency. here, we have tried to optimize the properties of ...
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Multidrug resistance proteins (MRPs) are members of the C family of a group of proteins named ATP-binding cassette (ABC) transporters. These ABC transporters together form the largest branch of proteins within the human body. The MRP family comprises of 13 members, of which MRP1 to MRP9 are the major transporters indicated to cause multidrug resistance in tumor cells by extruding anticancer dru...
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ژورنال
عنوان ژورنال: Drug Delivery System
سال: 2005
ISSN: 1881-2732,0913-5006
DOI: 10.2745/dds.20.49